What is the difference between bacopa and ginkgo biloba?
Bacosides, the active ingredients of Bacopa:
– have an antioxidant action
– have an agonistic effect on the 5HT1a receptors, which are the serotonin receptors known to be involved in memory processes.
– also increase the level of acetylcholine, the neurotransmitter of memory and learning.
– increase the level of γ-aminobutyric acid (GABA) which plays a vital role in adults by preventing prolonged excitation of neurons.
Bacopa helps focus (reduce distractibility) short-term memory and improves mood.
Ginkgo Biloba contributes to increasing oxygen levels in the brain. Indeed, in addition to its antioxidant activity, Ginkgo exerts a vasoregulatory activity on the whole vascular system: arteries, capillaries, veins.
It is also an inhibitor of platelet aggregation and therefore not recommended with anticoagulants.
What precautions should be taken when taking Optim Memory (bacopa/ brahmi and longvida curcumin)?
In the absence of relevant studies on the use of turmeric (curcumin) and bacopa during pregnancy and lactation, Optim Memory is not recommended in these cases.
Bacopa has been shown, albeit inconsistently, to have a mild sedative (calming) effect, so caution should be taken when used in combination with other known sedatives.
Precautions for people on neuroleptic (phenothiazine class) and hormonal (thyroid) therapy.
Does Bacopa have any side effects?
Bacopa has been safely used in Ayurvedic medicine for several hundred years. (Monograph Bacopa Monnieri 2004)
Bacopa with doses up to 100-200mg/day of bacosides are not associated with any known side effects (Asthana 1996)
Why combine longvida curcumin with Bacopa?
Longvida Curcumin has antioxidant and anti-inflammatory properties (Nahar 2014) and neuroprotective effects, as demonstrated by in-vivo and in-vitro studies (Goozee 2016).
Optim Memory’s Longvida® curcumin was developed by scientists at the University of California – Los Angeles (UCLA). Clinical studies have shown that the Longvida® formulation increases the bioavailability of curcumin in its active (free) form, which can cross the blood-brain barrier. (Gota 2010; Koronyo 2017)
A clinical study by the University of Swinburne has shown that Longvida® curcumin (400mg/day) significantly improves working memory and reduces mental fatigue. (Cox 2014)
Bacopa acts on neurotransmitters that stimulate concentration memory and contribute to better mental alertness.
Combining these two plant extracts makes it possible to act on several factors and thus improve cognitive functions.
What are the Bacoside levels in Optim Memory?
The Bacopa extract, Bacognize®, is standardised by HPLC, a very specific and accurate method of analysis.
Bacognize® contains 10% bacoside glycosides, namely bacoside A3, bacopasaponin C, bacopaside II, bacopaside X and bacopaside I. Bacognize® also contains a significant amount of flavonoids (such as luteolin and apigenin) and other polyphenols that act as antioxidants
Bacosides, the active ingredients of Bacopa, act positively on neurotransmitters. In particular, they increase:
– the serotonin level that is involved in memory processes.
– the level of acetylcholine, the neurotransmitter of memory and learning
– and the level of γ-aminobutyric acid (GABA), which plays a vital role in adults by preventing prolonged excitation of neurons. (Charles 2011; Rajan 2011)
Bacopa monnieri (l.) pennel or brahmi