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Butycaps Capsules - 60 capsules

€39,99

Take advantage of a discount based on the quantities purchased.
5% for two, 8% for three, 10% for four and 12% for more than five products.

Butycaps Capsules is a food supplement containing liquid tributyrin (soft-gel capsules)

60 capsules per box

Tributyrin supports intestinal transit and promotes proper intestinal functioning.

Lactose free Lactose-Free
Gluten freeGluten-Free
Made in SpainMade in Spain

Tributyrin (butyrin) is found naturally in butter. One molecule of butyrin provides three molecules of butyrate. 


Butyrin presents the advantage that it is better absorbed than butyrate salts (sodium butyrate).


Butyrin in liquid softgel capsules acts mainly along the entire intestine: small intestine and colon.


Butycaps Capsules contains 450 mg of butyrin per capsule, providing 394 mg of butyric acid/butyrate.


Tributyrin (butyrate) supports intestinal transit and promotes proper intestinal functioning.


Serving Size: 
1 to 2 capsules per day to be swallowed with a glass of water during a meal.

 

Precautions for use:

Food supplement only for adults (over 18 years old).

It is recommended to respect the recommended doses. Does not replace a varied and balanced diet and a healthy lifestyle. Keep out of reach of young children. Store in a dry place and away from direct sunlight.

List of ingredients per capsule: 
Butyrin (450mg), Coating: bovine gelatine; Humectant: glycerol; Medium Chain Triglycerides (MCT) from coconut oil; Humectant: water.


Gluten-free, lactose-free

 

Nutritional information:

Per capsule

1

2

Butyrin

450 mg

900 mg

 

Nutritional values per 100g:
Carbohydrates: 9g – Fat: 71g – Protein: 17g


Energy Value: 
Per 100g/: 732 Kcal / 3022 KJ

Net weight: 42 g (60 capsules - 3 blisters of 20 capsules)


Notification number (Belgium): AS_2708/9

CNK 4234-597 – EAN: 542503792013-1

What are Short-Chain Fatty Acids (SCFAs)?

In the colon, 90 -95% of the short-chain fatty acids are acetic acid (C2), propionic acid (C3) and butyrate / butyric acid (C4). SCFA are also called "postbiotic" as they are metabolites derived from the microbiota.

Indeed, these fatty acids are produced in the gut during the digestion of fibres and carbohydrates. The colon epithelium consumes almost all butyric acid, the main energy source for colonocytes.

On the other hand, both acetic and propionic acid passe into the blood (portal vein). They are used as precursors in the liver or peripheral tissues for gluconeogenesis and hepatic lipogenesis.


Short-chain fatty acids (SCFAs): metabolites of the microbiota

The bacteria that colonise the digestive tract, especially the colon, feed on the prebiotics we eat to reproduce. Prebiotics are food substances generally composed of carbohydrates (oligosaccharides and polysaccharides) but essential to the intestinal microbiota.
Indeed, the microbiota transforms these fibres into short-chain fatty acids (SCFAs). Among them, butyrate plays a crucial role in intestinal physiology, as it is one of the preferred sources of carbon in colon epithelial cells. Without butyrate, these cells would be in energy “deficiency”.



Which bacteria convert fibres into butyrate?

Several bacteria transforming fibres into butyrate have been identified: Anaerostipes spp. (A, L), Coprococcus catus (A), Eubacterium rectale (A), Eubacterium hallii (A, L), Faecalibacterium prausnitzii (A), Roseburia spp. (A) (Canani 2011; Koh 2016)


What is the relationship between butyrate and microbiota? How can I increase my butyrate level?

SCFAs are produced during colonic fermentation by bacteria from incompletely digested cellulosic residues and starches. The amount of SCFAs produced by this fermentation process is therefore dependent on the type of food individuals eat and the bacterial pool maintained in the colon.
Low prebiotic consumption or antibiotic use reduces the production of SCFAs, especially butyrate.

Biological roles of butyrate

First, SCFAs affect the gastrointestinal tract and ensure proper intestinal function.

Their primary function is to serve as an energy source for the cells in the colon. Butyrate is the primary energy source for colonocytes or the cells that form the colon wall. It allows them to multiply and function normally. Without these compounds, these cells undergo autophagy and eventually enter apoptosis and die.
Butyrate has an anti-inflammatory action, acts on intestinal motility (constipation and diarrhoea), stimulates the absorption of water and sodium, helps maintain the protective mucus layer of the intestine, and helps combat leaky gut. (Canani 2011)


What is the difference between butyric acid and butyrin?
There are salts of butyric acid. This form is rapidly absorbed in the intestine.

Tributyrin (triglyceride of butyric acid) is digested more slowly and allows a prolonged action in the intestine
Do you want to know more about the butyrate and its benefits?

Butycaps Sachets is produced in Spain in collaboration with our partner Elie Health Solutions.

The ingredients are thoroughly selected: 

- Gluten-free 

- GMO-free


Frequently Asked Questions

  • Is it butyrate safe?

    Butyric acid is a metabolite of fibre fermentation in the gut and is considered safe.

    In a clinical study with patients with Crohn's disease, taking twice 2 grams per day (4g) for 8 weeks was well tolerated and considered safe.

    Di Sabatino A, Morera R, Ciccociocioppo R, Cazzola P, Gotti S, Tinozzi FP, et al Oral butyrate for mildly to moderately active Crohn’s disease. Aliment Pharmacol Ther 2005;22(9):789-94.


  • Why take Butycaps during a meal?

    Butycaps contains butyrin triglycerides (fatty acids).

    It is, therefore, preferable to take Butycaps Capsules with a meal to facilitate digestion (production of bile and pancreatic enzymes) and the hydrolysis of triglycerides to fatty acids (butyric acid).


  • What is the difference between butyrate and probiotics or prebiotics?

    Prebiotics are non-digestible substances that serve as a substrate for colon flora. (oligosaccharides and short-chain polysaccharides)


    Probiotics
    are living micro-organisms (bacteria or yeasts).

    We speak of intestinal flora (or gut microbiota), i.e. all the micro-organisms (archaea, bacteria, eukaryotes) that are found in the digestive tract ( intestine and stomach). The intestinal flora is an excellent example of symbiosis.

    The intestinal microbiota produces butyric acid (butyrate) from fibres. Its production is enhanced by prebiotic agents (soluble fibres).


  • Does Butycaps contain lactose?

    Butycaps is lactose-free.

  • What is the difference between butyrate and glutamine?

    Glutamine is an amino acid that acts as an essential nutrient for various organs and tissues, such as muscles, immune cells, and intestinal cells.

    It is said to be an essential amino acid under certain conditions: in case of metabolic stress, for example, its consumption is very high by immune system cells. Therefore, in these situations, it is advisable to supplement with glutamine.

    Glutamine is also interesting for the intestine because some organs consume glutamine in large quantities when there is metabolic stress. There is a deficit in the intestine, which causes an increase in intestinal permeability.

    The fundamental difference is that butyrate is a specific nutrient of the intestine, while glutamine is a nutrient of the intestine and many other organs and tissues.

    Therefore, for glutamine to affect the intestine, substantial amounts are required.

    On the other hand, butyrate and glutamine are more synergistic than competitors.


  • References

    Canani RB, Costanzo MD, Leone L, Pedata M, Meli R, Calignano A. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol. 2011 28;17(12):1519-28.


    Koh A, De Vadder F, Kovatcheva-Datchary P, Bäckhed F. From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites. Cell. 2016 Jun 2;165(6):1332-1345. 


    Papillon E, Bonaz B, Fournet J. [Short chain fatty acids: effects on gastrointestinal function and therapeutic potential in gastroenterology]. Gastroenterol Clin Biol. 1999 Jun-Jul;23(6-7):761-9. Review.